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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7798e2c3bb9c4d82d82162290793f6a4e8a975787f901098e7318bb563963ee5' 
  AND token = '0Kv6+s7TJ2LQc0JOMEra9TStDeSQXBZPeJLYRWnM0hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}