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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca57905d7a7613ebbc01ae32ad7e7d7afc10d91785959bf0a29e64d78a05e95a' 
  AND token = 'yFJ7/TILQqVYWO2q2z4DMisOHOXW6R/OUdcxtEB8Qes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}