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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb610d0c7eb1803952fcd27a03c50ebb5fe185e1d1378b98f7fa67b0dce0c54' 
  AND token = 'HY+9KSUSwgyBnyKT+uXLKGLC9dgGkeJWtbGIPTxkiko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}