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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a8fbe0e89df6bc3b951ad7639e78ad9f7e320749e119431b47c6f1cb0bf852' 
  AND token = 'WmoWEWSATj7swmeqn5Z8UOAgwKAhB7WpN2rgcu+Oo7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}