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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8295c5234ed6604d61fe20c880eb25e140a7d1d9d414cf0ed0226372a40d433' 
  AND token = 'JefKv/l6wbjOx2qZTiPfeHcWoNPdhoK1nTxwldevTCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}