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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57da3d25b705e18d8f842334b98cadaf0c3dd50241610a1aa92e5d646da5f7e7' 
  AND token = 'wl00ir66AuvBEnbfyR4WQoClcIq1aIEa0ibSbbXJ4PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}