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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed1d68f8dd5cd47b85c221a9d580779295e69797095950dbb04ca197c59b8b9' 
  AND token = 'O05HIuuMTSbsNW8u/Z6tNU9RnayIXnwYoE8eksTjxU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}