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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd12ecab181bbbaa831ae162251e0d217fc8aa062efc580e4b63128f2b2e7343' 
  AND token = 'ZEcsfalZ17Y4pAQ8iDTJqtMWHrxDydLTEiTO1QyglFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}