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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc55c14ab04849415292a0aa8364cb595a3fc07ddfc1cf50cc2595d78cb61121' 
  AND token = '3n+4tWyd2pZv1cmvXmVAgbc+jlX8CyWVHdpWKRpfxDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}