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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a874199c937bf7d3abebc13fc04934e8f3c25bffca28e44af34d6b46b889f43' 
  AND token = '81nJvm+oWkwD9R9vajacWIRChGRauOxs1fiwmCyoiA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}