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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a197585ae57da99e6bc0a531d58da31275d122a8f5e715aedd817254b27ce3' 
  AND token = 'HJCF0Cczs3dVfS5dJRjcmqNHO9XYxOY0+G6aLeucleg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}