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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecfc5f6f3f872ce23b2814e7f453f400a74be57a0a48e77c5829e851eb0e571' 
  AND token = 'yIkGWMDcUwvr7dYH0+hGGNczWiarokalPYuggnFXdR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}