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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb6f52d7afcdf0b68a49359cf7114df175e87b63b2307badd50e0d7d47bb304' 
  AND token = 'fLrRYqA2x+XMtc6+XW0n/65vwKRFiFq4Z0m9TWvDopA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}