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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed112120a8329e1087f1214744ba7355c359ce1bb3dd7a6cc6d60da3ca34c22' 
  AND token = 'bkgpy2moBY/u6bb0UY+68LrKDsYZGDQhXnS8dBjeaRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}