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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ed6a9c9bcfc489e62d243ef600000716480801afaa77396264fdae9c3f41df' 
  AND token = 'jGwqbP2VZ+oOR19dutZgh0bkF9OitwHtcIM2IUU6V9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}