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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3b0db3bed3c43831389ead228dc2b3f4da23947cd53d66ba6a220cfc30ac04' 
  AND token = '1tZS6HWr8lhj3PeZWgXBPEQ6DyLUwrsjCpl4xLGdWmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}