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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac3c773104d0de55d348b38db7bff569d9b6554c08892df7387400e1d436e566' 
  AND token = 'Fwfz+PyH3FzVIwIWB1SjE3VG9qCkDgteMIwS3BnXLDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}