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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b44956f4b1f6fdb1f3a84a3e521002bf49e3003213e324ea748597c0d2a4f4' 
  AND token = 'geDoyfHOG0mDmTLwsuun49kEndBLeci/FsCrkSw91Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}