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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149a011891c381c4e1bc6ad9294749abe466a90d48df2f52d72a8a56179a8a5f' 
  AND token = 'lP4X3u3MVAbBPEJyNXkf5kHP85UFO+zDvieAGB5DwiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}