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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f258083386ff8f58c8d5ccbbbe551d669f3d5e93f9cc1680c63e88a5150c9f67' 
  AND token = 'cTcx5KWhB6wm+dKiCCsrZMEdEQ/y3DYzeW1lSvbirXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}