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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b92dead70f73776ca2acee4bb0d6e395b315b9b79320e1b9215ef384296a7d' 
  AND token = 'NfL/A3ZZuO70c5zAtS07vJQG2mXnjkVK6GXnbMCCKCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}