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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac9b4fdbb9e1781831ed65b21e53006f3685879d8677b23bef9b3aec6bcbe490' 
  AND token = '3qAN0ieno1ewqIMK0TjR7TQQ5VoX6eyDf+UFmj/Rs9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}