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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78475e0e7b49c34e444d30768ad067c8a087aadeafaddb5a337b96c26a68613' 
  AND token = 'wzW3Ksy/yWqgMIut+Ukj0LF+lNRrI28adp/wix4lmfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}