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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1789a0c285ace9241dc8a28e6bef15e1d9327b05573584b5a378e29d1af0f58' 
  AND token = 'fu+BzuBHLkx6/yzHkIvuupSQXkzTQbdWs2ny4eWCnjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}