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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7f77d97dfea5251f79266d52b19da00bf6823f0661f78fec091ce51115f8c52' 
  AND token = 'DHpoLvUW89PZgDfCUznOpko87KTH+ofjl6cXNNJ8HYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}