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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e75a6d86ea9212d2fa198a4a91f7de2bf0a7a14be76e371de150315a5d5985d' 
  AND token = '49a3obatUCL4uJ+rYyBnyNyHbtpF1f1YC634A9mhLvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}