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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd709bc4ef0ac5109a6e2369a1a4fba12d1a43c69dbd2f7872fdfc7cebfd73227' 
  AND token = 'P+9FDUhUPWFSqcTmU6tZeAH0aomTDav1tQRrDRgasR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}