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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7b149a01c73e491ef0108583f6bebbc37225fcbb2a2a73141c0a1b0295ab4a' 
  AND token = 'Z0TwAQ8FFQJnrQxh3gLi1s8pCa9uNr9WDHWvkphgHJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}