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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5754b3906bc2395206ab35697c1b9d3ce3c0e81c80322ff37681a913301bf681' 
  AND token = 'eNS7jBODrHFlY0dWdxnxoH0hjACdjT2F5wHTwn0rQ9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}