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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9053879956f9abc452f205c537c1fef672afd576eeef226fb1739422a07b396' 
  AND token = 'XGWJrSDic+Ts//aEMtjAKOO+mg20UTmpiFcJOER0kZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}