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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b483faa14afe0a4075c4fc9edcb9be43e86786304a242f28727911e7ffaea2e0' 
  AND token = 'cOOYK9zfnqHWxm4FbkcBNnanTqE6rS4deBN4B+UF+Mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}