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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278df92d4c94d7f09e00a5f85113bd1f9313d5a88c8a028cf9fbe041f3f16fab' 
  AND token = 'KMAgpM7oE6Ov3iWW6LCP8ETRU5FPt3sAKLpkWC6oLjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}