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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb64f3e54dcb756a4a6baaa713a96c6e73f335d99b4f52b3cd28a16e25966d5' 
  AND token = '5lNmqlYV4jRod9zuCInLEohRq2lQ/DE96dcGMUiJ+sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}