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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678e248811f0647601841edad767a8941cd11d0cd2a59be027eba3d527098fb0' 
  AND token = 'JEjIfMhOsQIB3o5cOr6QG8dBoNQWsQfv1y07QNRosiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}