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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '167793bb434e00da90c6dc906e19cc59aa426cc4bc89ec06eb7466651ef58ebb' 
  AND token = 'EzbS8UEa3xov4p3GaVm62x/mbscxxW4cFeswcezzH00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}