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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1642645cad5886a04eb58f0cd522b80587112987f43ba5bcdd7a8e54cdb5a76' 
  AND token = 'tpaM/QejzIcmVcp7X5rK4cKG2hB97QkWu7rynDHA6Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}