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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e21f56c39a50d88464539548762fd8d8eef66914371b969e4b9ad9ab8861acb7' 
  AND token = 'R/7BPiO+OcDij3J3CTUUTokbousVT3VxeI2EvJ9CgcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}