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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '239573ecf0489e9fb5005eab623c4b294e99e59738b9e72a50f037393680fbe1' 
  AND token = 'dlV3kSQBmyNwC+IwexzbBM0GtqZEy5KIh7pvbtsBU7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}