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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6951b0816dd85f04abe64b7762213c5d4b3d6395108e903dcf43ac79ea4d4948' 
  AND token = 'JwTJ6ZnKiJ3OjZcufhyUjy18YpLy8XFzyjH9in3LCt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}