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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49509a74c43266542f7fdb2e338e7c73fff51b747d9e72bf687561eac294627e' 
  AND token = 'ltdlYpUbwp93Knbq58nIQUY2L1+UNVT6n2Nos2FRCm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}