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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e14ef2db27840c2fe3ee21ebba92c0fcbc4f83ebe3fd29dde0e290e28c33d7' 
  AND token = 'hor60BqQx3o1ELgUhTo8S7XWmiEptkRYgOv74RUITsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}