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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1f1139566e39f9d2e661b52a6edbe354a53217290a90c56638ea41c5c2b999' 
  AND token = 'jpPzWiDcpN8Wfv8K8IobdVbvhWy7pE4r+nrnzjaH1d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}