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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de001392a8ecadbfcda0b656dffd4642eb38e7022051bf2e83cc6d5989a99edc' 
  AND token = 'jc8zbzifaS3WZOpOmTYB5NlogVzgAHzRM3YmK3P7uXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}