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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a565f0c74f22d6b00e653bea4d2e88d91ca274ad2b0ba94d145844394b0236d' 
  AND token = 'sp5mZvL050tYdYxvfgAtF9zEYHPjS23ddZCRziqx9mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}