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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f77b6db9c04ad5b189bd50b80d0b0e762115d7b7182de42162203b82248e6b' 
  AND token = 'FHt89fO0N29M0ZChIXzitAi0zLzYPZOSGMM0lzT8WZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}