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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd35d4f9e1d9a76581811be0f65bab6722a60fab23fc886458cd1994b0f18a40b' 
  AND token = 'k5f6jJmOKsffbgpAF0jfYHSqWsXhPw8E3ZTHkpOcYHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}