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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da52953df63a71f7c82bbd7b895e4a677cb4d8577ad8fb08898c1f94312312c0' 
  AND token = 'SWdOrSS7gb1We96FaFs6Z24Koa0WKOLnmzhSns/s8lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}