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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1295efe990541d52daadb92c47ce03c1ddac0f17139534d226249847214db52' 
  AND token = 'le752xrB1kANgFB00Uk8FrKGkmgltrUmw1tOsdslJ5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}