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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bb5c1e50c3e8f00e5a940a9c2276990b959d698a439b9126520855b1c910917' 
  AND token = 'EayUfr8wl3DXN9stLO8ropyuuIvg+I8gErQ14gkDVx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}