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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cc9db6a77b31e4fee57143c24df1e8af7214511ecdfe4164a422c5e7699ecf' 
  AND token = '3+GS/wvPNNFJWurNS/JiApiWCi9u2uNv6k3nvyJZxoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}